Asymmetric hydrogenation of heteroaromatic compounds
- PMID: 17896823
- DOI: 10.1021/ar700094b
Asymmetric hydrogenation of heteroaromatic compounds
Abstract
Asymmetric hydrogenation of heteroaromatic compounds has emerged as a promising new route to saturated or partially saturated chiral heterocyclic compounds. In this Account, we outline recent advances in asymmetric hydrogenation of heteroaromatic compounds, including indole, quinoline, isoquinoline, furan, and pyridine derivatives, using chiral organometallic catalysts and organocatalysts.
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