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. 2008 Jan 1;16(1):400-4.
doi: 10.1016/j.bmc.2007.09.024. Epub 2007 Sep 18.

Design of a pyrene-containing fluorescence probe for labeling of RNA poly(A) tracts

Kazuo Tanaka  1 , Akimitsu Okamoto
Affiliations

Design of a pyrene-containing fluorescence probe for labeling of RNA poly(A) tracts

Kazuo Tanaka et al. Bioorg Med Chem. .

Abstract

A labeling probe containing a pyrenecarboxamide-tethered modified DNA base, (Py)U, has been developed for fluorometric detection of RNA poly(A) tracts, in which the fluorescence emission intensity was controlled by the microstructural change around (Py)U caused by binding with the target RNA.

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