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Case Reports
. 2007 Nov;11(3):471-3.
doi: 10.1016/j.yebeh.2007.06.012. Epub 2007 Sep 27.

Pregabalin-induced generalized myoclonic status epilepticus in patients with chronic pain

S Knake  1 , K M Klein, K Hattemer, A Wellek, W H Oertel, H M Hamer, F Rosenow
Affiliations
Case Reports

Pregabalin-induced generalized myoclonic status epilepticus in patients with chronic pain

S Knake et al. Epilepsy Behav. 2007 Nov.

Abstract

Pregabalin is often used for the treatment of chronic pain syndromes. We here describe two patients with chronic pain and pregabalin-induced myoclonic status epilepticus. Patients treated with pregabalin who experience sudden behavioral changes or mycloni should be investigated for this possible side effect, and pregabalin should be reduced or discontinued if myocloni or status epilepticus occurs.

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