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. 2008 Apr;10(2):110-4.
doi: 10.1016/j.jfms.2007.07.002. Epub 2007 Oct 1.

Measuring statistical agreement between four point of care (POC) lactate meters and a laboratory blood analyzer in cats

Mark J Acierno  1 , Meghan E Johnson, Lee Ann Eddleman, Mark A Mitchell
Affiliations

Measuring statistical agreement between four point of care (POC) lactate meters and a laboratory blood analyzer in cats

Mark J Acierno et al. J Feline Med Surg. 2008 Apr.

Abstract

The use of blood lactate concentrations as a prognostic indicator and therapeutic gauge in feline medicine has been hindered by the inability to obtain values in a timely manner with minimal quantities of blood. Recently, hand-held point-of-care (POC) lactate meters have become commercially available. The objective of this prospective study was to determine if lactate values produced by three commercially available and one medical grade POC meter were in agreement with a laboratory blood analyzer. Blood samples from 47 cats were collected on presentation to an emergency service and processed on four POC meters and a Stat Profile Critical Care Xpress blood analyzer. The results were analyzed using the Bland-Altman method. The blood lactate values produced by the hospital grade POC meter and one of the commercially POC meters were in good agreement with the Critical Care Xpress blood analyzer. Other commercially available POC meters produced acceptable agreement.

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Figures

Fig 1.
Fig 1.
Bland–Altman plot. The difference between the measurements (iSTAT−Critical Care Express) plotted for the mean of the values measured by the two methods ([iSTAT+Critical Care Express]/2).
Fig 2.
Fig 2.
Bland–Altman plot. The difference between the measurements (Lactate pro−Critical Care Express) plotted for the mean of the values measured by the two methods ([Accutrend+Critical Care Express]/2).
Fig 3.
Fig 3.
Bland–Altman plot. The difference between the measurements (Lactate scout−Critical Care Express) plotted for the mean of the values measured by the two methods ([Lactate scout+Critical Care Express]/2).
Fig 4.
Fig 4.
Bland–Altman plot. The difference between the measurements (Accutrend−Critical Care Express) plotted for the mean of the values measured by the two methods ([Accutrend+Critical Care Express]/2).
See this image and copyright information in PMC

References

    1. Acierno M., Mitchell M. Evaluation of four point-of-care meters for rapid determination of blood lactate concentrations in dogs, Journal of the American Veterinary Medical Association 230, 2007, 1315–1318. - PubMed
    1. Bland J.M., Altman D.G. Statistical methods for assessing agreement between two methods of clinical measurement, Lancet 1, 1986, 307–310. - PubMed
    1. Bland J.M., Altman D.G. Measuring agreement in method comparison studies, Statistical Methods in Medical Research 8, 1999, 135–160. - PubMed
    1. Boldt J., Kumle B., Suttner S., Haisch G. Point-of-care (poc) testing of lactate in the intensive care patient. Accuracy, reliability, and costs of different measurement systems, Acta Anaesthesiologia Scandavia 45, 2001, 194–199. - PubMed
    1. de Papp E., Drobatz K.J., Hughes D. Plasma lactate concentration as a predictor of gastric necrosis and survival among dogs with gastric dilatation-volvulus: 102 cases (1995–1998), Journal of the American Veterinary Medical Association 215, 1999, 49–52. - PubMed