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Comparative Study
. 2007 Oct;21(5):655-8.
doi: 10.1053/j.jvca.2007.01.012. Epub 2007 Apr 11.

Evaluation of partial carbon dioxide rebreathing cardiac output measurement during thoracic surgery

Affiliations
Comparative Study

Evaluation of partial carbon dioxide rebreathing cardiac output measurement during thoracic surgery

Ju-Mei Ng et al. J Cardiothorac Vasc Anesth. 2007 Oct.

Abstract

Objective: Noninvasive partial CO2 rebreathing (NICO; Novametrix Medical Systems, Inc, Wallingford, CT) is a relatively new alternative to thermodilution (TDCO) for measurement of cardiac output. This study compares the 2 methods during thoracic surgery and one-lung ventilation.

Design: A prospective, observational study.

Setting: A tertiary hospital.

Participants: Twelve adult patients undergoing elective thoracotomy and one-lung ventilation in the lateral decubitus position.

Interventions: Paired measurements of cardiac output were performed during (1) 2-lung ventilation in the supine position (postinduction of anesthesia), (2) 10 minutes after initiation of one-lung ventilation in the lateral decubitus position with the nondependent chest open, and (3) after 30 minutes on one-lung ventilation. An average of 3 consecutive (10 mL 20 degrees C saline) TDCO measurements made during end-expiration was compared with corresponding NICO measurements.

Measurements and main results: The NICO showed a tendency to underestimate cardiac output compared with TDCO at all measurement times. Overall, bias was -0.29 L/min and limits of agreement -1.69 to 1.43 L/min.

Conclusions: There was a moderate agreement between cardiac output measurements obtained with the NICO and TDCO. The present data suggest that the NICO technique may be useful during thoracic surgery.

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