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. 1991 Sep 14;201(1-2):27-33.
doi: 10.1016/0009-8981(91)90021-4.

Bone-alkaline phosphatase as indicator of bone formation

J P van Straalen  1 , E Sanders, M F Prummel, G T Sanders
Affiliations

Bone-alkaline phosphatase as indicator of bone formation

J P van Straalen et al. Clin Chim Acta. .

Abstract

Bone-alkaline phosphatase was determined in patients at risk of osteoporosis due to treatment with oral corticosteroids, and in patients at risk of increased bone synthesis because of treatment with cyclosporin. Both a significant decrease of bone-alkaline phosphatase during corticosteroid treatment, and a significant increase of bone-alkaline phosphatase during cyclosporin treatment could be demonstrated. It is concluded that bone-alkaline phosphatase is a useful parameter for monitoring changes in bone formation.

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