Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Apr;30(2):161-8.
doi: 10.1007/s11096-007-9157-4. Epub 2007 Sep 29.

Minimising treatment-associated risks in systemic cancer therapy

Ulrich Jaehde  1 , Andrea Liekweg, Sven Simons, Martina Westfeld
Affiliations
Review

Minimising treatment-associated risks in systemic cancer therapy

Ulrich Jaehde et al. Pharm World Sci. 2008 Apr.

Abstract

Aim of the review: To review the consequences of drug-related problems (DRP) in systemic cancer therapy and identify specific contributions of the pharmacist to minimise treatment-associated risks.

Method: Searches in PubMed, Embase and the Cochrane Library were conducted. Bibliographies of retrieved articles were examined for additional references. Only papers in English between 1980 and 2007 were included.

Results: In systemic cancer therapy there is an enormous potential for DRP due to the high toxicity and the complexity of most therapeutic regimens. The most frequently reported DRP can be classified into adverse effects, drug-drug interactions, medication errors, and non-adherence. Pharmacists have enhanced efforts to assure quality and safety in systemic cancer therapy together with other health care providers. In consequence, oncology pharmacy has evolved as a novel specialist discipline. The endeavour to merge and co-ordinate individual activities and services of the pharmacist has led to pharmaceutical care concepts which aim at offering novel solutions to the various DRP.

Conclusion: Pharmaceutical care for cancer patients should be developed within research projects and integrated into disease management programs in order to ensure broad implementation.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Medication event monitoring system, MEMSTM: The pill bottle cap contains a micro-electronic circuit that registers when the bottle is opened. This data may then be transferred to a computer via a reading device
See this image and copyright information in PMC

References

    1. None
    2. Knox RA. Doctor’s orders killed cancer patient. Boston Globe 1995;23:1 Metro/Region.
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1007/s00520-003-0539-4', 'is_inner': False, 'url': 'https://doi.org/10.1007/s00520-003-0539-4'}, {'type': 'PubMed', 'value': '14530957', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/14530957/'}]}
    2. Liekweg A, Westfeld M, Jaehde U. From oncology pharmacy to pharmaceutical care: new contributions to multidisciplinary cancer care. Support Care Cancer 2004;12:73–9. - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1177/1078155206070412', 'is_inner': False, 'url': 'https://doi.org/10.1177/1078155206070412'}, {'type': 'PubMed', 'value': '16984745', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/16984745/'}]}
    2. Bremberg ER, Hising C, Nylen U, Ehrsson H, Eksborg S. An evaluation of pharmacist contribution to an oncology ward in a Swedish hospital. J Oncol Pharm Pract 2006;12:75–81. - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'PubMed', 'value': '15064936', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/15064936/'}]}
    2. Lau PM, Stewart K, Dooley M. The ten most common adverse drug reactions (ADRs) in oncology patients: do they matter to you? Support Care Cancer 2004;12:626–33. - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1016/0277-5379(83)90418-2', 'is_inner': False, 'url': 'https://doi.org/10.1016/0277-5379(83)90418-2'}, {'type': 'PubMed', 'value': '6681766', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/6681766/'}]}
    2. Coates A, Abraham S, Kaye SB, Sowerbutts T, Frewin C, Fox RM, et al. On the receiving end-patient perception of the side-effects of cancer chemotherapy. Eur J Cancer Clin Oncol 1983;19:203–8. - PubMed

Publication types

MeSH terms