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. 1991;37(4):287-91.
doi: 10.1159/000238869.

Nephrotoxicity of aminoglycosides, polypeptides and cephalosporins in cancer patients

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Nephrotoxicity of aminoglycosides, polypeptides and cephalosporins in cancer patients

V Krcméry Jr et al. Chemotherapy. 1991.

Abstract

The nephrotoxicity of various combinations of antibiotics--aminoglycosides, cephalosporins, vancomycin, amphotericin B--in 171 oncologic patients is described. The most nephrotoxic combination seems to be cefotaxime plus gentamicin, ceftriaxone plus amikacin and amphotericin B with cephalosporin, vancomycin or aminoglycoside. Less toxic was netilmicin with penicillin or cephalosporin, and vancomycin.

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