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Case Reports
. 2007:27:90-4.

Pigmented villonodular synovitis in children: a report of six cases and review of the literature

Philip Neubauer  1 , A Kristy Weber, Nancy Hadley Miller, Edward F McCarthy
Affiliations
Case Reports

Pigmented villonodular synovitis in children: a report of six cases and review of the literature

Philip Neubauer et al. Iowa Orthop J. 2007.

Abstract

We report six children with pigmented villonodular synovitis. They ranged in age from seven to fifteen years. In four patients, the knee was involved. One patient had involvement of the ankle, and one had diffuse involvement along a metacarpal. In five cases, the diagnosis was not suspected clinically or radiographically, and the delay in making the correct diagnosis was as long as two years. Clinical diagnosis in these five patients was usually bacterial synovitis or juvenile rheumatoid arthritis. We feel that the diagnoses of pigmented villonodular synovitis should be considered in any child with chronic joint effusion.

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Conflict of interest statement

Each author certifies that he or she has no commercial associations (e.g. consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article.

Each author certifies that his or her institution approved the reporting of this case series, that all investigations were conducted in conformity with ethical principles of research, and that informed consent was obtained.

Figures

Figure 1
Figure 1
A T2-weighted MRI of knee of patient two. There is an effusion and synovial thickening in the anterior portion of the joint.
Figure 2
Figure 2
A T1-weighted MRI of the knee of patient three. There is an intraarticular mass in the posterior aspect of the joint.
Figure 3
Figure 3
A T2-weighted MRI of the knee of patient four. There is significant effusion in periarticular bursae as well as diffuse synovial thickening.
Figure 4
Figure 4
A T1-weighted MRI of the ankle of patient six. The mass in the anterior portion of the joint shows signal dropout consistent with PVNS. There is also a chondral defect in the dome of the talus.
Figure 5
Figure 5
Photomicrograph of the lesion of patient six. Mononuclear cells characteristic of PVNS contain hemosiderin (H&E, x120).
See this image and copyright information in PMC

References

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