Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2007 Oct;6(4):247-9.
doi: 10.1016/j.cmet.2007.09.004.

Silencing insulin resistance through SIRT1

Janice M Zabolotny  1 , Young-Bum Kim
Affiliations
Free article
Comment

Silencing insulin resistance through SIRT1

Janice M Zabolotny et al. Cell Metab. 2007 Oct.
Free article

Abstract

Insulin resistance is an important risk factor for the development of type 2 diabetes and the metabolic syndrome. A new study in this issue of Cell Metabolism (Sun et al., 2007) shows that SIRT1, a mammalian sirtuin homolog and histone deacetylase, can ameliorate insulin resistance by silencing expression of protein tyrosine phosphatase 1B, a major negative regulator of insulin action.

PubMed Disclaimer

Comment on

LinkOut - more resources