Nationwide increase in the number of hospitalizations for illicit injection drug use-related infective endocarditis
- PMID: 17918083
- PMCID: PMC2567828
- DOI: 10.1086/522176
Nationwide increase in the number of hospitalizations for illicit injection drug use-related infective endocarditis
Abstract
Infective endocarditis is a potentially fatal consequence of illicit injection drug use. We estimate that the number of hospitalization for injection drug use-related infective endocarditis increased by 38%-66% in the United States between 2000-2001 and 2002-2003, a period during which the number of at-risk persons (i.e., injection drug users) remained stable. Increasing methamphetamine use and/or drug injection frequency may have increased the incidence of infective endocarditis among active injection drug users.
Comment in
-
Buprenorphine diversion: a possible reason for increased incidence of infective endocarditis among injection drug users? The Singapore experience.Clin Infect Dis. 2008 Mar 15;46(6):953-5; author reply 955-6. doi: 10.1086/528869. Clin Infect Dis. 2008. PMID: 18288906 No abstract available.
References
-
- Frontera JA, Gradon JD. Right-sided endocarditis in injection drug users: review of proposed mechanisms of pathogenesis. Clin Infect Dis. 2000;30:374–9. - PubMed
-
- US Department of Health and Human Services, National Center for Health Statistics, National Hospital Discharge Survey, 2001. ICPSR version. Hyattsville, MD: US Department of Health and Human Services, National Center for Health Statistics; 2001.
-
- National Hospital Discharge Survey Description. 2007. [Accessed 16 January 2007]. Available at: http://www.cdc.gov/nchs/about/major/hdasd/nhdsdes.htm.
-
- Cooper HL, Wypij D, Krieger N. Police drug crackdowns and hospitalization rates for illicit-injection–related infections in New York City. Internat J Drug Policy. 2005;16:150–60.
-
- Louria D, Sen P, Sherer C, Farrer W. Infections in older patients: a systematic clinical approach. Geriatrics. 1993;48:28–34. - PubMed
