Comment
doi: 10.1016/j.neuron.2007.09.019.
The ups and downs of neural progenitors: Cep120 and TACCs control interkinetic nuclear migration
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- PMID: 17920006
- DOI: 10.1016/j.neuron.2007.09.019
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Comment
The ups and downs of neural progenitors: Cep120 and TACCs control interkinetic nuclear migration
Neuron.
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Abstract
The nuclei of dividing neural progenitors undergo a cell-cycle-dependent change in position along the apico-basal axis known as interkinetic nuclear migration (INM). The functional relationship between INM and the mode of division of neural progenitors remains elusive, in part because its regulation at the molecular level is poorly understood. In this issue of Neuron, Xie et al. identify two centrosomal proteins (Cep120 and TACCs) regulating the INM of cortical neural progenitors.
Comment on
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Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.Neuron. 2007 Oct 4;56(1):79-93. doi: 10.1016/j.neuron.2007.08.026. Neuron. 2007. PMID: 17920017 Free PMC article.
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