Loss of T-bet sends host-microbe mutualism awry
- PMID: 17923080
- DOI: 10.1016/j.cell.2007.09.030
Loss of T-bet sends host-microbe mutualism awry
Abstract
Immune homeostasis in the intestine involves complex interactions between microbial organisms and host cells. In this issue, Garrett et al. (2007) describe a communicable form of colitis that is induced by deficiency of the transcription factor T-bet in cells of the innate immune system.
Comment on
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Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system.Cell. 2007 Oct 5;131(1):33-45. doi: 10.1016/j.cell.2007.08.017. Cell. 2007. PMID: 17923086 Free PMC article.
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