Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Dec;16(12):2159-65.
doi: 10.1007/s00586-007-0444-5. Epub 2007 Oct 9.

StabilimaxNZ) versus simulated fusion: evaluation of adjacent-level effects

Manohar M Panjabi  1 , Gweneth Henderson, Yue James, Jens Peter Timm
Affiliations

StabilimaxNZ) versus simulated fusion: evaluation of adjacent-level effects

Manohar M Panjabi et al. Eur Spine J. 2007 Dec.

Abstract

Rationale behind motion preservation devices is to eliminate the accelerated adjacent-level effects (ALE) associated with spinal fusion. We evaluated multidirectional flexibilities and ALEs of StabilimaxNZ and simulated fusion applied to a decompressed spine. StabilimaxNZ was applied at L4-L5 after creating a decompression (laminectomy of L4 plus bilateral medial facetectomy at L4-L5). Multidirectional Flexibility and Hybrid tests were performed on six fresh cadaveric human specimens (T12-S1). Decompression increased average flexion-extension rotation to 124.0% of the intact. StabilimaxNZ and simulated fusion decreased the motion to 62.4 and 23.8% of intact, respectively. In lateral bending, corresponding increase was 121.6% and decreases were 57.5 and 11.9%. In torsion, corresponding increase was 132.7%, and decreases were 36.3% for fusion, and none for StabilimaxNZ ALE was defined as percentage increase over the intact. The ALE at L3-4 was 15.3% for StabilimaxNZ versus 33.4% for fusion, while at L5-S1 the ALE were 5.0% vs. 11.3%, respectively. In lateral bending, the corresponding ALE values were 3.0% vs. 19.1%, and 11.3% vs. 35.8%, respectively. In torsion, the corresponding values were 3.7% vs. 20.6%, and 4.0% vs. 33.5%, respectively. In conclusion, this in vitro study using Flexibility and Hybrid test methods showed that StabilimaxNZ stabilized the decompressed spinal level effectively in sagittal and frontal planes, while allowing a good portion of the normal rotation, and concurrently it did not produce significant ALEs as compared to the fusion. However, it did not stabilize the decompressed specimen in torsion.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Photographs. a Bilateral application of the StabilimaxNZ® and b the multidirectional spine tester
Fig. 2
Fig. 2
Results of flexibility testing in three planes. a Intervertebral ranges of motion (iROM) in degrees at L4–L5 for the Intact, Decompression, StabilimaxNZ® and simulated fusion. Statistical significance with respect to the Intact are indicated by asterisks (*). b The iROM at L4–L5 in percentage of the Intact
Fig. 3
Fig. 3
Results of Hybrid testing in flexion–extension. Adjacent-level effects (ALE) due to a StabilimaxNZ® and b simulated fusion. For the definition of ALE, please see text
Fig. 4
Fig. 4
Results of Hybrid testing in bilateral lateral bending. Adjacent-level effects (ALE) due to a StabilimaxNZ® and b simulated fusion. For the definition of ALE, please see text
Fig. 5
Fig. 5
Results of Hybrid testing in bilateral torsion. Adjacent-level effects (ALE) due to a StabilimaxNZ® and b simulated fusion. For the definition of ALE, please see text
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1097/00007632-199011010-00011', 'is_inner': False, 'url': 'https://doi.org/10.1097/00007632-199011010-00011'}, {'type': 'PubMed', 'value': '2267608', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/2267608/'}]}
    2. Abumi K, Panjabi MM, Kramer KM, et al (1990) Biomechanical evaluation of lumbar spinal stability after graded facetectomies. Spine 15:1142–1147 - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'PubMed', 'value': '16381209', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/16381209/'}]}
    2. Ames CP, Acosta FL Jr, Chamberlain RH, Larios AE, Crawford NR (2005) Biomechanical analysis of a newly designed bioabsorbable anterior cervical plate. Invited submission from the joint section meeting on disorders of the spine and peripheral nerves, March 2005. J Neurosurg Spine 3:465–470 - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1016/S0140-6736(99)01312-4', 'is_inner': False, 'url': 'https://doi.org/10.1016/s0140-6736(99)01312-4'}, {'type': 'PubMed', 'value': '10470716', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/10470716/'}]}
    2. Andersson GB (1999) Epidemiological features of chronic low-back pain. Lancet 354:581–585 - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1097/00007632-200211010-00004', 'is_inner': False, 'url': 'https://doi.org/10.1097/00007632-200211010-00004'}, {'type': 'PubMed', 'value': '12438979', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/12438979/'}]}
    2. Cunningham BW, Lewis SJ, Long J, et al (2002) Biomechanical evaluation of lumbosacral reconstruction techniques for spondylolisthesis: an in vitro porcine model. Spine 27:2321–2327 - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'PMC', 'value': 'PMC3611574', 'is_inner': False, 'url': 'https://pmc.ncbi.nlm.nih.gov/articles/PMC3611574/'}, {'type': 'PubMed', 'value': '12384732', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/12384732/'}]}
    2. Cunningham BW, Lowery GL, Serhan HA, et al (2002) Total disc replacement arthroplasty using the AcroFlex lumbar disc: a non-human primate model. Eur Spine J 11(Suppl 2):S115–S123 - PMC - PubMed

Publication types

MeSH terms