Concomitant Creutzfeldt-Jakob and Alzheimer diseases
- PMID: 1792870
- DOI: 10.1007/BF00294437
Concomitant Creutzfeldt-Jakob and Alzheimer diseases
Abstract
We report a 69-year-old female with cerebral and cerebellar symptomatology of 15-month duration. At autopsy, both panencephalopathic Creutzfeldt-Jakob and plaque-predominant Alzheimer diseases were found. Plaque amyloid was exclusively of the beta/A4 type, but abundant abnormal protease-resistant protein was identified by Western blot analysis of brain extracts.
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