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Case Reports
. 1991;83(1):95-8.
doi: 10.1007/BF00294437.

Concomitant Creutzfeldt-Jakob and Alzheimer diseases

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Case Reports

Concomitant Creutzfeldt-Jakob and Alzheimer diseases

J M Powers et al. Acta Neuropathol. 1991.

Abstract

We report a 69-year-old female with cerebral and cerebellar symptomatology of 15-month duration. At autopsy, both panencephalopathic Creutzfeldt-Jakob and plaque-predominant Alzheimer diseases were found. Plaque amyloid was exclusively of the beta/A4 type, but abundant abnormal protease-resistant protein was identified by Western blot analysis of brain extracts.

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