Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2007 Nov;66(11):1409-10.
doi: 10.1136/ard.2007.076463.

Optimal use of methotrexate: the advantages of tight control

J W J Bijlsma, M E Weinblatt
Editorial

Optimal use of methotrexate: the advantages of tight control

J W J Bijlsma et al. Ann Rheum Dis. 2007 Nov.

Abstract

The CAMERA study shows that using methotrexate in a tight control setting might lead to considerable improvement in disease activity in early rheumatoid arthritis See linked article p 1443.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Comment on

References

    1. O'Dell J R. The BeSt way to treat early rheumatoid arthritis? Ann Intern Med 2007146459–460. - PubMed
    1. O'Dell J R. Treating rheumatoid arthritis early: a window of opportunity? Arthritis Rheum 200246283–285. - PubMed
    1. VanderHeide A, Jacobs J W, Bijlsma J W, Heurkens A H, VanBooma‐Frankfort C, VanderVeen M J.et al The effectiveness of early treatment with “second‐line” antirheumatic drugs. A randomized controlled trial. Ann Intern Med 1996124699–707. - PubMed
    1. Mottonen T, Hannonen P, Leirisalo‐Repo M, Nissila M, Kautiainen H, Korpela M.et al Comparison of combination therapy with single‐drug therapy in early RA: a randomized trial. FIN‐RACo trial group. Lancet 19993531568–1573. - PubMed
    1. van Everdingen A A, Jacobs J W, Siewertsz van Reesema D R, Bijlsma J W. Low dose prednisone therapy for patients with early active rheumatoid arthritis: clinical efficacy, disease‐modifying properties, and side effects: a randomized, double‐blind, placebo controlled clinical trial. Ann Intern Med 20021361–12. - PubMed

MeSH terms