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. 2007 Nov 8;9(23):4761-4.
doi: 10.1021/ol702110k. Epub 2007 Oct 17.

Synthesis of a promising immunosuppressant: FR252921

Dominique Amans  1 , Véronique Bellosta, Janine Cossy
Affiliations

Synthesis of a promising immunosuppressant: FR252921

Dominique Amans et al. Org Lett. .

Abstract

A concise and highly convergent synthesis of the promising immunosuppressant FR252921 was achieved by using optically active titanium complexes to control the configuration of the three stereogenic centers.

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