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Review
. 2007 Sep-Nov;74(2-3):159-71.
doi: 10.1016/j.mvr.2007.08.005. Epub 2007 Sep 7.

Therapeutic myocardial angiogenesis

Marie-Ange Renault  1 , Douglas W Losordo
Affiliations
Review

Therapeutic myocardial angiogenesis

Marie-Ange Renault et al. Microvasc Res. 2007 Sep-Nov.

Abstract

Armed with an improved understanding of the mediators of angiogenesis, physicians and scientists have made significant efforts at harnessing this naturally occurring process in order to treat patients with a variety of peripheral vascular and coronary ischemic syndromes. There is a growing population of patients with end-stage coronary artery disease (CAD) who are no longer candidates for mechanical revascularization, yet suffer from chronic myocardial ischemia who may benefit from regeneration of the depleted microvasculature.

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