Weight gain with atypical antipsychotics: evidence and insights

Abstract

Weight gain associated with antipsychotic medication can be a barrier to the overall improvement of mental health patients due to a discontinuation of treatment. The goal of this article is to establish a better understanding regarding the mechanisms of antipsychotic medications and their associated risk of weight gain, obesity, and subsequent mortality and morbidity. Additionally, the need to closely monitor patients' lifestyles and homeostatic components in order to prevent weight gain or facilitate weight loss is emphasized.