Review
doi: 10.1002/pauz.200700242.
[On chance discovery in rational drug design. Aspergillus fumigatus and angiogenesis]
[Article in
German]
Affiliations
- PMID: 17957690
- DOI: 10.1002/pauz.200700242
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Review
[On chance discovery in rational drug design. Aspergillus fumigatus and angiogenesis]
[Article in
German]
Pharm Unserer Zeit.
2007.
Abstract
Der Schimmelpilz Aspergillus fumigatus produziert einen potenten Angiogenesehemmstoff, das Fumagillin. Diese Substanz war einer der ersten niedermolekularen Angiogeneseinhibitoren und trug wesentlich dazu bei, diese therapeutische Strategie überhaupt erst interessant zu machen.
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