Eat less, live longer? New insights into the role of caloric restriction in the brain
- PMID: 17958208
- DOI: 10.1111/j.1753-4887.2007.tb00319.x
Eat less, live longer? New insights into the role of caloric restriction in the brain
Abstract
Caloric restriction has wide-ranging health benefits and may offer protection against age-related neuronal loss and neurodegenerative disorders such as Alzheimer's disease, possibly via enhanced adult neurogenesis. While a variety of interventions such as exercise increase neurogenesis, recent work suggests that exercise and caloric restriction may work to enhance neurogenesis by different neurobiological mechanisms, suggesting a role for both diet and exercise in disease prevention.
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