Genomics and proteomics methodologies for vulnerable populations research
- PMID: 17958293
Genomics and proteomics methodologies for vulnerable populations research
Abstract
This chapter describes common genomic and proteomic methods and their application to the study of vulnerable population groups. The International HapMap project is discussed in relation to unique Haplotype single nucleotide polymorphisms (htSNPs) in population groups. In addition, studies, which have used these methods to investigate aging, ethnic, and racial specific conditions, as well as psychiatric diseases, are reviewed. Advantages and limitations of various genomic and proteomic approaches are discussed in relation to population admixture and sample selection.
Similar articles
-
Strength in numbers.Nature. 2005 Jul 28;436(7050):492-3. doi: 10.1038/436492a. Nature. 2005. PMID: 16089007 No abstract available.
-
Time runs short for HapMap.Nature. 2007 May 17;447(7142):242-3. doi: 10.1038/447242c. Nature. 2007. PMID: 17507945 No abstract available.
-
[International HapMap project].Nihon Rinsho. 2005 Dec;63 Suppl 12:29-34. Nihon Rinsho. 2005. PMID: 16416767 Review. Japanese. No abstract available.
-
Differences in disease frequency between Europeans and Polynesians: directions for future research into genetic risk factors.Pac Health Dialog. 2001 Mar;8(1):129-56. Pac Health Dialog. 2001. PMID: 12017815 Review.
-
Relaxed rules open path to genomic data on disease.Nature. 2004 Dec 16;432(7019):788. doi: 10.1038/432788b. Nature. 2004. PMID: 15602509 No abstract available.
Cited by
-
Searching for the noninvasive biomarker holy grail: are urine proteomics the answer?Biol Res Nurs. 2011 Jul;13(3):235-42. doi: 10.1177/1099800411402056. Epub 2011 May 17. Biol Res Nurs. 2011. PMID: 21586496 Free PMC article. Review.