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. 1991 Sep-Oct;25(5):35-40.

[Interspecies mouse-mink hybridomas as producers of mink immunoglobulin]

[Article in Russian]
  • PMID: 1796509

[Interspecies mouse-mink hybridomas as producers of mink immunoglobulin]

[Article in Russian]
E G Ufimtseva et al. Tsitol Genet. 1991 Sep-Oct.

Abstract

The work is aimed at establishing the interspecies mouse-mink hybridomas from the fusion of American mink B-lymphocytes with the murine cell line NSO. The hybridoma (lime 10-B5) continued to secrete mink immunoglobulin L-chains in the culture for 6 months with constant reclonings. The hybridoma clone was characterized by a decrease in the secretory activity of cells. The karyological study et this clone has not reliably revealed the mink chromosomes in the genome of hybrid cells.

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