Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Sep;4(3):351-3.
doi: 10.1093/ecam/nel099.

In vitro anti-Candida Activity of Zataria multiflora Boiss

Ali Zarei Mahmoudabadi  1 , Muhammad Ali Dabbagh, Zahra Fouladi
Affiliations

In vitro anti-Candida Activity of Zataria multiflora Boiss

Ali Zarei Mahmoudabadi et al. Evid Based Complement Alternat Med. 2007 Sep.

Abstract

Zataria multiflora Boiss known as Avishan Shirazi (in Iran) is one of the valuable Iranian medicinal plants. The aim of study was to evaluate anti-Candida activity of Z. multiflora against different species of Candida in vitro. Anti-Candida activity of the aqueous, ethanolic and methanolic maceration extract of the aerial parts of Z. multiflora Boiss was studied in vitro. Anti-Candida activity against Candida species was done using serial dilutions of extracts in Sabouraud's dextrose agar. Minimal inhibitory concentration (MIC) of the methanolic and ethanolic extracts was 70.7 and 127 mg l(-1), respectively. Aqueous extract showed no remarkable activity against Candida species. We conclude that methanolic extract of the aerial parts of Z. multiflora Boiss has more anti-Candida effect at 70.7 mg l(-1) compared to ethanolic extract 127 mg l(-1). In addition, the isolates of Candida parapsilosis were more susceptible to methanolic extract than other tested species.

Keywords: Candida; Zataria multiflora Boiss; anti-Candida; herbal medicine.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Ali MS, Saleem M, Ali Z, Ahmad VU. Chemistry of Zataria multiflora (Lamiaceae) Phytochemistry. 2000;55:933–6. - PubMed
    1. Mohagheghzadeh A, Shams-Ardakani M, Ghannadi A, Minaeian M. Rosmarinic acid from Zataria multiflora tops and in vitro cultures. Fitoterapia. 2004;75:315–21. - PubMed
    1. Mohagheghzadeh A, Shams-Ardakani M, Ghannadi A. Linalol-rich essential oil of Zataria multiflora Boiss (Lamiaceae) Flavour Fragrance J. 1999;15:119–22.
    1. Mohagheghzadeh A, Shams-Ardakani M, Ghannadi A. Volatile constitutes of callus and flower-bearing tops of Zataria multiflora Boiss (Lamiaceae) Flavour Fragrance J. 2000;15:373–6.
    1. Javidnia K, Tabatabai M, Shafiee A. Volatile constituents and antimicrobial activity of Zataria multiflora, population Iran. Irn J Chem Chem Eng. 1999;18:1–5.

LinkOut - more resources