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Review
. 2007 Oct 26;3(10):1372-3.
doi: 10.1371/journal.ppat.0030147.

Pathogenesis, virulence, and infective dose

Paul Schmid-Hempel  1 , Steven A Frank
Affiliations
Review

Pathogenesis, virulence, and infective dose

Paul Schmid-Hempel et al. PLoS Pathog. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests. The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Dose and Mode of Pathogenic Mechanism
Upper panel: bacteria with pathogenic mechanisms that depend on direct contact (local action). Lower panel: bacteria with pathogenic mechanisms that depend on secreted molecules (distant action). Dose information is from the US Food and Drug Administration [2] and Health Canada [3]. Various sources include references [–14]. Values for Yersinia are considered low by the US Food and Drug Administration, while Health Canada refers to LD50 in mice.
See this image and copyright information in PMC

References

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    1. United States Food and Drug Administration. The bad bug book. 2003. Available: http://www.cfsan.fda.gov/~mow/intro.html. Accessed 26 September 2007.
    1. Health Canada. Material safety data sheets. 2003. Available: http://www.phac-aspc.gc.ca/msds-ftss/index.html. Accessed 26 September 2007.
    1. Donnenberg MS. Pathogenic strategies of enteric bacteria. Nature. 2000;406:768–774. - PubMed
    1. Salyers AA, Whitt DD. Bacterial pathogenesis. 2nd edition. Washington (D. C.): ASM Press; 2002.