Review
doi: 10.1016/j.immuni.2007.10.005.
T helper 17 cells get the NOD
Affiliations
- PMID: 17967409
- DOI: 10.1016/j.immuni.2007.10.005
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Review
T helper 17 cells get the NOD
Immunity.
2007 Oct.
Free article
Abstract
Interleukin-17 (IL-17)-producing helper T cells play a role in pathogen defense and autoimmunity. In this issue of Immunity, van Beelen et al. (2007) reveal a pathway that elicits potent IL-17 production from memory T cells through activation of the intracellular receptor NOD2.
Comment on
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Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells.Immunity. 2007 Oct;27(4):660-9. doi: 10.1016/j.immuni.2007.08.013. Epub 2007 Oct 4. Immunity. 2007. PMID: 17919942
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