Review
Considerations for generic oncology FDG-PET/CT protocol preparation in drug development
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- PMID: 17968761
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Review
Considerations for generic oncology FDG-PET/CT protocol preparation in drug development
IDrugs.
2007 Nov.
Abstract
[18F]Fluorodeoxyglucose (FDG)-PET combined with CT is increasingly being used as an imaging tool in oncology clinical trials. Progress in the standardization and harmonization of acquisition and analysis protocols for FDG-PET/CT has been made, although there are still areas for which further guidance is needed. Standardizing FDG-PET/CT clinical trial design and interpretation will contribute to increased efficiency and precision in decision-making for drug development. This feature review highlights areas in FDG-PET/CT imaging, particularly image analysis and response classification, that currently require expert guidance or further research to optimize the application of this tool in oncological drug development.
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