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Review
. 1991 Sep;13(9):429-37.
doi: 10.1002/bies.950130902.

The molecular basis for tropomyosin isoform diversity

J P Lees-Miller  1 , D M Helfman
Affiliations
Review

The molecular basis for tropomyosin isoform diversity

J P Lees-Miller et al. Bioessays. 1991 Sep.

Abstract

The tropomyosins are a family of actin filament binding proteins. In multicellular animals, they exhibit extensive cell type specific isoform diversity. In this essay we discuss the genetic mechanisms by which this diversity is generated and its possible significance to cellular function.

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