Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2008 Jan;23(1):131-4.
doi: 10.1002/mds.21783.

Pallidal deep brain stimulation improves quality of life in segmental and generalized dystonia: results from a prospective, randomized sham-controlled trial

Joerg Mueller, Inger M Skogseid, Reiner Benecke, Andreas Kupsch, Thomas Trottenberg, Werner Poewe, Gerd H Schneider, Wilhelm Eisner, Alexander Wolters, J U Müller, Günther Deuschl, Marcus O Pinsker, Geir K Roeste, Juliane Vollmer-Haase, Angela Brentrup, Martin Krause, Volker Tronnier, Alfons Schnitzler, Jüergen Voges, Guido Nikkhah, Jan Vesper, Markus Naumann, Jens Volkmann; Deep-Brain Stimulation for Dystonia Study Group
Collaborators
Randomized Controlled Trial

Pallidal deep brain stimulation improves quality of life in segmental and generalized dystonia: results from a prospective, randomized sham-controlled trial

Joerg Mueller et al. Mov Disord. 2008 Jan.

Abstract

As part of the first randomized, sham-stimulation controlled trial on deep brain stimulation (DBS) in primary segmental or generalized dystonia, health-related quality of life (HRQoL) was assessed by SF-36. After the 3-month sham-controlled phase, significant HRQoL improvement occurred only in the active-stimulation group. The open-label extension phase resulted in a significant improvement in all SF-36 domains following 6 months of neurostimulation. These results demonstrate a favorable impact of DBS on HRQoL in primary dystonia.

PubMed Disclaimer

Publication types