Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1976 Jun 11;101(24):920-3.
doi: 10.1055/s-0028-1104188.

[VIP and GIP-producing pancreatic tumour: relationship to the Verner-Morrison syndrome]

[Article in German]
H Kunert, F M Kuhn, K Schwemmle, R Ottenjann
Case Reports

[VIP and GIP-producing pancreatic tumour: relationship to the Verner-Morrison syndrome]

[Article in German]
H Kunert et al. Dtsch Med Wochenschr. .

Abstract

A 59-year-old man had explosive watery diarrhoea, tendency towards collapse, flushes and aphonia. Pre-operative serum concentrations of vasoactive intestinal polypeptide (VIP) were up to 1030 ng/l, those of gastric inhibitory polypeptide (GIP) up to 2675 ng/l, as measured by radioimmunoassay. Cross-reaction by antisera used in the radioimmunoassay were excluded. Pancreatic tumour was diagnosed by ultrasound and by elective coeliac arteriography. After excision the abnormal fidings disappeared as did the symptoms. Biological half-life of plasma-VIP (determined during removal of the tumour from plasma samples by radioimmunoassay) was about 45 minutes. The tumour produced both VIP and GIP.

PubMed Disclaimer

Similar articles

See all similar articles

LinkOut - more resources