LH-RH-sensitive adenylate cyclase in isolated plasma membranes of rat adenohypophyses
- PMID: 179783
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LH-RH-sensitive adenylate cyclase in isolated plasma membranes of rat adenohypophyses
Endocrinol Exp.
1975 Jan.
Abstract
The adenylate cyclase system in isolated plasma membranes of rat adenohypophyses was studied. Formation of cAMP was found to be dependent on plasma membrane protein. Production of cAMP could be stimulated by the addition of LH-RH. This process was shown to be a function of LH-RH concentration. Basal and stimulated cAMP could be stimulated by NaF. The results of the present experiments suggest that cAMP formation is time dependent. The synthesis of cAMP is a possible effector of LH-RH actions.
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