doi: 10.1016/j.bmcl.2007.10.017.
Epub 2007 Oct 17.
Syntheses of novel myxopyronin B analogs as potential inhibitors of bacterial RNA polymerase
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- PMID: 17980587
- DOI: 10.1016/j.bmcl.2007.10.017
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Syntheses of novel myxopyronin B analogs as potential inhibitors of bacterial RNA polymerase
Bioorg Med Chem Lett.
.
Abstract
Based upon observations from our initial findings, additional myxopyronin B analogs have been prepared and tested for in vitro inhibitory activity against DNA-dependent RNA polymerase and antibacterial activity against Escherichia coli and Staphylococcus aureus.
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