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Comment
. 2007 Nov 2;131(3):443-5.
doi: 10.1016/j.cell.2007.10.023.

alphaPlGF: a new kid on the antiangiogenesis block

Rakesh K Jain  1 , Lei Xu
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alphaPlGF: a new kid on the antiangiogenesis block

Rakesh K Jain et al. Cell. .
Free article

Abstract

An agent that blocks tumor angiogenesis, growth, and metastasis without affecting normal tissues -- whether used alone or in combination with currently approved drugs -- would change the way we treat cancer. In this issue, Fischer et al. (2007) offer compelling evidence that a monoclonal antibody against placental growth factor (PlGF), a member of the VEGF family, has such potential in mice.

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