A second-generation combined linkage physical map of the human genome
- PMID: 17989245
- PMCID: PMC2099587
- DOI: 10.1101/gr.7156307
A second-generation combined linkage physical map of the human genome
Abstract
We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v.2, includes 28,121 polymorphic markers with physical positions corroborated by recombination-based data. Sex-averaged and sex-specific linkage map distances, along with confidence intervals, have been estimated for all map intervals. In addition, a regression-based smoothed map is provided that facilitates interpolation of positions of unmapped markers on this map. With nearly twice as many markers as our first-generation map, the Rutgers Map continues to be a unique and comprehensive resource for obtaining genetic map information for large sets of polymorphic markers.
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- R01 GM080221/GM/NIGMS NIH HHS/United States
- K25 AA015346/AA/NIAAA NIH HHS/United States
- R01 HG002651/HG/NHGRI NIH HHS/United States
- HG003229/HG/NHGRI NIH HHS/United States
- HG002651/HG/NHGRI NIH HHS/United States
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- MH068457/MH/NIMH NIH HHS/United States
- Z01 HG000040/ImNIH/Intramural NIH HHS/United States
- GM080221/GM/NIGMS NIH HHS/United States
- R01 HG003229/HG/NHGRI NIH HHS/United States
- T32 HG000040/HG/NHGRI NIH HHS/United States
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