The challenges of managing cancer related venous thromboembolism in the palliative care setting
- PMID: 17989265
- PMCID: PMC2659959
- DOI: 10.1136/pgmj.2007.061622
The challenges of managing cancer related venous thromboembolism in the palliative care setting
Abstract
Cancer patients with venous thromboembolism (VTE) pose particular management challenges since they have an increased risk of bleeding and recurrent thrombosis compared to the non-cancer population. Also, as the disease progresses so do the hazards of anticoagulation, and patients in the palliative stages of their cancer could be viewed as a separate disease group with respect to diagnosis and management. As the focus from curative treatment moves towards symptom control, physicians face several challenges in providing the most appropriate care. Palliative care patients have rarely been included in research on VTE and the supporting evidence needs to be extrapolated cautiously. Quality of life aspects of VTE and their management may be a more appropriate outcome measure in this stage of disease than radiological end points. This paper looks at the challenges facing professionals in the management of VTE in the advanced cancer patient.
Conflict of interest statement
Competing interests: None
References
-
- Trousseau A. Phlegmasia alba dolens. In: Clinique Medicale d'Hotel‐Dieu de Paris, vol 3. Paris: JB Balliere et Fils 1865654–812.
-
- Bick R L. Alterations of haemostasis with malignancy. Semin Thromb Hemost 197851–26. - PubMed
-
- Johnson M J, Sproule M W, Paul J. The prevalence and associated variables of deep venous thrombosis in patients with advanced cancer. Clin Oncol 199911105–110. - PubMed
-
- Ambrus J L, Ambrus C M, Pickren J W. Causes of death in cancer patients. J Med 1975661–64. - PubMed
-
- Sproul E E. Carcinoma and venous thrombosis: the frequency of association of carcinoma in the body or tail of the pancreas with multiple venous thrombosis. Am J Cancer 193834566–585.
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