Review
doi: 10.1016/j.molcel.2007.10.016.
Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination
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- PMID: 17996697
- DOI: 10.1016/j.molcel.2007.10.016
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Review
Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination
Mol Cell.
.
Free article
Abstract
In a recent issue of Molecular Cell, Limbo et al. (2007) identify a new homologous recombination factor, Ctp1 in S. pombe, a homolog of Sae2/Com1 in S. cerevisiae and CtIP in mammals, that operates cooperatively with the MRN complex.
Comment on
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Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination.Mol Cell. 2007 Oct 12;28(1):134-46. doi: 10.1016/j.molcel.2007.09.009. Mol Cell. 2007. PMID: 17936710 Free PMC article.
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