Review
doi: 10.1016/j.molcel.2007.10.013.
AROuSing SIRT1: identification of a novel endogenous SIRT1 activator
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- PMID: 17996699
- DOI: 10.1016/j.molcel.2007.10.013
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Review
AROuSing SIRT1: identification of a novel endogenous SIRT1 activator
Mol Cell.
.
Free article
Abstract
SIRT1 is a protein deacetylase that regulates cellular responses to a variety of stresses. In a recent issue of Molecular Cell, Kim et al. (2007) report the identification of a cellular protein, AROS, that activates the SIRT1-mediated deacetylation of p53.
Comment on
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Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity.Mol Cell. 2007 Oct 26;28(2):277-90. doi: 10.1016/j.molcel.2007.08.030. Mol Cell. 2007. PMID: 17964266
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