Comment
doi: 10.1016/j.chom.2007.04.004.
A Reverse genetics system for dsRNA viruses
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- PMID: 18005686
- DOI: 10.1016/j.chom.2007.04.004
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Comment
A Reverse genetics system for dsRNA viruses
Cell Host Microbe.
.
Free article
Abstract
The advent of a new reverse genetics system for reoviruses, described in this issue of Cell Host & Microbe by Kobayashi et al., opens new horizons of investigation into the molecular mechanisms governing dsRNA virus replication and pathogenesis. The elegant approach for recombinant reovirus recovery from a set of plasmid DNAs provides a template for designing similar reverse genetics systems for other dsRNA viruses associated with considerable morbidity and mortality in humans.
Comment on
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A plasmid-based reverse genetics system for animal double-stranded RNA viruses.Cell Host Microbe. 2007 Apr 19;1(2):147-57. doi: 10.1016/j.chom.2007.03.003. Cell Host Microbe. 2007. PMID: 18005692 Free PMC article.
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