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. 2004 Apr 30;9(5):323-9.
doi: 10.3390/90500323.

1-Hydroxymethyl-4-phenylsulfonybutadiene, a versatile building block for the synthesis of 2,3,4-trisusbtituted tetrahydrothiophenes

David Díez  1 , M Templo Benéitez, Isidro S Marcos, N M Garrido, P Basabe, Julio G Urones
Affiliations

1-Hydroxymethyl-4-phenylsulfonybutadiene, a versatile building block for the synthesis of 2,3,4-trisusbtituted tetrahydrothiophenes

David Díez et al. Molecules. .

Abstract

A method to synthesize chiral 2,3,4-trisusbtituted tetrahydrothiophenes in both enantiomerically pure forms starting from 1-hydroxymethyl-4-phenylsulfonylbutadiene is described.

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Scheme 1
Scheme 1
Scheme 2
Scheme 2
Scheme 3
Scheme 3
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References

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