Mammalian sperm chromatin structure and assessment of DNA fragmentation
- PMID: 18008155
- PMCID: PMC3455000
- DOI: 10.1007/s10815-007-9177-y
Mammalian sperm chromatin structure and assessment of DNA fragmentation
Abstract
This review article illustrates the biology of mammalian sperm chromatin structure. The possible causes of DNA (deoxyribonucleic acid) fragmentation are discussed. Also available molecular techniques for assessment of mammalian sperm DNA damage are described.
References
-
- Lewis SE, Aitken RJ. DNA damage to spermatozoa has impacts on fertilization and pregnancy. Cell Tissue Res. 2005;322:33–41. - PubMed
-
- Zini A, Bielcki R, Phang D, Zenzes MT. Correlations between two markers of sperm DNA integrity, DNA denaturation and DNA fragmentation in fertile and infertile men. Fertil Steril. 2001;75:674–7. - PubMed
-
- Evenson DP, Larson KL, Jost LK. Sperm chromatin structure assay: its clinical use for detecting sperm DNA fragmentation in male fertility and comparisons with other techniques. J Androl. 2002;23:25–43. - PubMed
-
- Fuentes-Mascorro G, Serrano H, Rosado A. Sperm chromatin. Arch Androl. 2000;45:215–25. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources