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Review
. 2007 Nov-Dec;25(6):535-46.
doi: 10.1016/j.clindermatol.2007.08.007.

Psoriasis: epidemiology

Johann E Gudjonsson  1 , James T Elder
Affiliations
Review

Psoriasis: epidemiology

Johann E Gudjonsson et al. Clin Dermatol. 2007 Nov-Dec.

Abstract

Psoriasis is a chronic, inflammatory and hyperproliferative skin disease with a genetic basis. While epidermal hyperplasia and altered keratinocyte differentiation are prominent features, considerable evidence indicates that psoriasis is immunologically mediated. Recently, the identification of HLA-Cw6 as the disease allele conferring susceptibility to psoriasis has provided a focus for elucidation of these events. In this article, we will focus on the epidemiology of psoriasis and its associated arthritis.

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