Comment on

• A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells.

  Awasthi A, Carrier Y, Peron JP, Bettelli E, Kamanaka M, Flavell RA, Kuchroo VK, Oukka M, Weiner HL. Awasthi A, et al. Nat Immunol. 2007 Dec;8(12):1380-9. doi: 10.1038/ni1541. Epub 2007 Nov 11. Nat Immunol. 2007. PMID: 17994022
• Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells.

  Fitzgerald DC, Zhang GX, El-Behi M, Fonseca-Kelly Z, Li H, Yu S, Saris CJ, Gran B, Ciric B, Rostami A. Fitzgerald DC, et al. Nat Immunol. 2007 Dec;8(12):1372-9. doi: 10.1038/ni1540. Epub 2007 Nov 11. Nat Immunol. 2007. PMID: 17994023
• TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology.

  McGeachy MJ, Bak-Jensen KS, Chen Y, Tato CM, Blumenschein W, McClanahan T, Cua DJ. McGeachy MJ, et al. Nat Immunol. 2007 Dec;8(12):1390-7. doi: 10.1038/ni1539. Epub 2007 Nov 11. Nat Immunol. 2007. PMID: 17994024