Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2007 Dec;158(10):724-36.
doi: 10.1016/j.resmic.2007.09.009. Epub 2007 Oct 6.

Annotation, comparison and databases for hundreds of bacterial genomes

Claudine Médigue  1 , Ivan Moszer
Affiliations
Free article
Review

Annotation, comparison and databases for hundreds of bacterial genomes

Claudine Médigue et al. Res Microbiol. 2007 Dec.
Free article

Abstract

The multitude of bacterial genome sequences being determined has opened up a new field of research, that of comparative genomics. One role of bioinformatics is to assist biologists in the extraction of biological knowledge from this data flood. Software designed for the analysis and functional annotation of a single genome have, in consequence, evolved towards comparative genomics tools, bringing together the information contained in numerous genomes simultaneously. This paper reviews advances in the development of bacterial annotation and comparative analysis tools, and progress in the design of novel database structures for the integration of heterogeneous biological information.

PubMed Disclaimer

Comment in

  • Microbial genomics.
    Glaser P, Chandler M, Rocha E. Glaser P, et al. Res Microbiol. 2007 Dec;158(10):721-3. doi: 10.1016/j.resmic.2007.10.003. Epub 2007 Nov 5. Res Microbiol. 2007. PMID: 18082580 No abstract available.

LinkOut - more resources