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. 2008 Jan;46(1):321-4.
doi: 10.1128/JCM.02097-07. Epub 2007 Nov 21.

Optochin resistance among Streptococcus pneumoniae strains colonizing healthy children in Portugal

Sónia Nunes  1 , Raquel Sá-Leão, Hermínia de Lencastre
Affiliations

Optochin resistance among Streptococcus pneumoniae strains colonizing healthy children in Portugal

Sónia Nunes et al. J Clin Microbiol. 2008 Jan.

Abstract

Two percent of 1,973 pneumococcus strains isolated from carriers since 2001 in Portugal were found to be optochin resistant. These strains belonged to eight serotypes (and some were nontypeable), and they had diverse genetic backgrounds. Novel optochin-resistant lineages were detected over time, suggesting that there was a continuous, although sporadic, emergence of optochin resistance.

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Figures

FIG. 1.
FIG. 1.
Dendrogram of optochin-resistant pneumococci. I, subpopulation isolated from the inhibition zone close to the optochin disk; O, subpopulation isolated from the farthest zone from the halo; NT, nontypeable; PG, penicillin; Ery, erythromycin; Da, clindamycin; Tet, tetracycline; SXT, trimethoprim-sulfamethoxazole; Chl, chloramphenicol.
See this image and copyright information in PMC

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