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. 2008 Jan;26(1):1-4.
doi: 10.1016/j.tibtech.2007.10.006. Epub 2007 Nov 26.

A better fluorescent protein for whole-body imaging

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A better fluorescent protein for whole-body imaging

Robert M Hoffman. Trends Biotechnol. 2008 Jan.

Abstract

Whole-body imaging with fluorescent proteins is a powerful technology with many applications in small animals. Brighter, red-shifted proteins can make whole-body imaging more sensitive owing to reduced absorption by tissues and less scatter. A new protein called Katushka has been isolated. It is the brightest known protein with emission at wavelengths longer than 620 nm. This new protein offers the potential for noninvasive whole-body imaging of numerous cellular and molecular processes in live animals.

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