Qualitative analysis of an HIV transmission model

Abstract

In 1988, a multiple-group model for HIV transmission with preferred mixing was proposed by Jacquez and coworkers. In the present paper, the work done by Jacquez et al. is extended. It is shown that the stability modulus of the Jacobian matrix at the no-disease equilibrium is a threshold for this model. Furthermore, if the no-disease equilibrium is unstable, the number of infected individuals will remain above a certain positive level regardless of initial levels; that is, the disease will persist uniformly. The stability of the endemic equilibrium in the case of restricted mixing is also studied. A series of sufficient conditions for local and global asymptotic stability of the endemic equilibrium are stated.