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Review
. 2007 Dec;72(12):1419-21.
doi: 10.1038/sj.ki.5002654.

Inhibition of TGF-beta expression: a novel role for thiazolidinediones to implement renoprotection in diabetes

N Perico  1 , G Remuzzi
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Free article
Review

Inhibition of TGF-beta expression: a novel role for thiazolidinediones to implement renoprotection in diabetes

N Perico et al. Kidney Int. 2007 Dec.
Free article

Abstract

Actual strategies to delay progression of diabetic nephropathy provide imperfect protection when started late in the course of the disease. Ohtomo et al. now demonstrate that thiazolidinedione treatment was associated with a remarkable improvement in proteinuria and renal function, offering a new potential treatment for diabetic nephropathy.

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