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Review
. 2006;1(3):261-5.
doi: 10.2147/ciia.2006.1.3.261.

Orthomolecular medicine: the therapeutic use of dietary supplements for anti-aging

Affiliations
Review

Orthomolecular medicine: the therapeutic use of dietary supplements for anti-aging

Michael Janson. Clin Interv Aging. 2006.

Abstract

Dietary supplements at high doses as part of medical therapy have been controversial, but the evidence suggests that they play a significant role in prevention and treatment of diseases as well as protection from accelerated aging that results from oxygen free-radical damage, inflammation, and glycation. This literature review examines several supplements that have documented roles in medical therapy, including vitamins C and E, coenzyme Q10, alpha-lipoic acid, chromium, L-carnitine, and quercetin. The evidence shows benefits in diabetes, cardiovascular disease, hypertension, congestive heart failure, age-related deterioration of brain function and vision, and immune function, as well as other age-related health problems.

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Figures

Figure 1
Figure 1
Leukocyte vitamin C during infections. High dose vitamin C (6 g daily before and during infection) enhances leukocyte ascorbate levels at baseline and during infections. Low dose supplements (200 mg daily) have less pronounced effects.

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