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Case Reports
. 2008 Jan;17(1):57-60.
doi: 10.1097/MCD.0b013e3282beb59e.

Three siblings with Woodhouse-Sakati syndrome in an Indian family

George Koshy  1 , Sumita Danda, Nihal Thomas, Vikram Mathews, Vijay Viswanathan
Affiliations
Case Reports

Three siblings with Woodhouse-Sakati syndrome in an Indian family

George Koshy et al. Clin Dysmorphol. 2008 Jan.

Abstract

Woodhouse-Sakati syndrome consists of alopecia, hypogonadism, diabetes mellitus, mild mental retardation, sensorineural deafness and ECG abnormalities. The proband described here has the above-mentioned features and presented with idiopathic thrombocytopenic purpura not reported before. Phenotypic variability is present in the three affected siblings. The two sisters have hypergonadotropic hypogonadism and the brother has hypogonadotropic hypogonadism. Camptodactyly of fourth and fifth fingers is seen in proband and her brother. We report for the first time three affected siblings of Woodhouse-Sakati syndrome in an Indian family.

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References

    1. Al-Swailem SA, Al-Assiri AA, Al-Torbak AA 2006. Woodhouse Sakati syndrome associated with bilateral keratoconus. Br J Ophthalmol 90:116–117.
    1. Gul D, Ozata M, Mergen H, Odabasi Z, Mergen M 2000. Woodhouse and Sakati Syndrome (MIM 241080): report of a new patient. Clin Dysmorphol 9:123–125.
    1. Oerter KE, Friedman TC, Anderson HC, Casserole FG 1992. Familial syndrome of endocrine and neuroectodermal abnormalities. Am J Med Genet 44:487–491.
    1. Woodhouse NJY, Sakati NA 1983. A syndrome of hypogonadism, alopecia, diabetes mellitus, mental retardation deafness and ECG abnormalities. J Med Genet 20:216–219.

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