Should we include connection domain mutations of HIV-1 reverse transcriptase in HIV resistance testing
- PMID: 18052605
- PMCID: PMC2100139
- DOI: 10.1371/journal.pmed.0040346
Should we include connection domain mutations of HIV-1 reverse transcriptase in HIV resistance testing
Abstract
The author discusses a new study that found a common mutation in the connection domain of reverse transcriptase, a mutation that confers resistance to two antiretroviral drug classes.
Conflict of interest statement
Comment on
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N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance.PLoS Med. 2007 Dec;4(12):e335. doi: 10.1371/journal.pmed.0040335. PLoS Med. 2007. PMID: 18052601 Free PMC article.
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